High-Dose
Vitamin B6
Bioactive PLP

Name: Vitamin B6 PLP 25mg High-Dose
SKU: N5268CGB
Price: 9.90 GBP
Availability: InStock

4-MONTH SUPPLY

SKU

N5268CGB

Directly bioactive vitamin B6 in the form of PLP (pyridoxal 5'-phosphate). High-dose vitamin B6, 25mg per capsule, suitable for individuals with very high vitamin B6 requirements. With the addition of premium gum arabic as a natural filler, a well tolerated, natural and sustainably cultivated food source for intestinal bacteria. Vegan, no additives. 120 capsules

High-dose vitamin B6: 25mg per capsule
Ideal for individuals with high vitamin B6 requirements
Vitamin B6 in the form of bioactive PLP (pyridoxal 5'-phosphate)
PLP is the directly bioactive coenzyme form of vitamin B6
Vitamin B6 supports the nervous and immune systems and contributes to energy, protein, glycogen and homocysteine metabolism and cysteine synthesis
Vitamin B6 aids in the formation of red blood cells, reduces tiredness and fatigue and regulates hormone activity as well as the psyche
Natural gum arabic as the only other ingredient

In stock

Vitamin B6 in the form of bioactive PLP (pyridoxal 5'-phosphate)
High-dose vitamin B6: 25mg PLP per capsule
PLP is the directly bioavailable coenzyme form of vitamin B6, required in numerous metabolic reactions
Ultra-pure, 100% vegan
High-quality, natural filler: gum arabic cultivated without the use of plant protection products

Vitamin B6 is present as a variety of different active compounds. Pyridoxine, which is the form that most manufacturers use, is not actually biologically active until converted by the body. We have therefore chosen pyridoxal 5'-phosphate (PLP) as the active ingredient in our formulation, the directly active coenzyme form of vitamin B6, which the body can use directly in all important metabolic pathways.

Our premium PLP is a pure, high-quality and vegan active ingredient with the highest possible bioavailability.

The only other ingredient is premium gum arabic, cultivated without the use of plant protection products. In contrast to microcrystalline cellulose, a widely used synthetic filler often mixed with nanoparticles, gum arabic is a natural, fibre-rich food. Our fair trade gum arabic is climate neutral and is sustainably cultivated to conserve resources.

For the capsule shells we use custom-made HPMC capsules that, unlike most other HPMC and pullulan capsules on the market, are 100% free from controversial additives such as carrageenans and PEG. We then package this product in environmentally friendly amber glass.

Premium active ingredients in their purest form
Sourced directly from the world’s best producers
Our select raw materials are the basis of all our formulations
Complete avoidance of all unnecessary additives and adjuvants
Exclusive use of valuable natural ingredients for additives
We voluntarily declare all ingredients
All extractions performed without the use of chemical solvents
Custom production when necessary, in order to achieve the highest possible level of purity
Independent laboratory testing available on product pages
Raw materials sourced only from premium suppliers who are committed to fair working conditions
Amber glass and compostable pouches used for packaging
Vegan capsule shells, free from PEG and carrageenans
Packaged in the EU according to HACCP, GMP and ISO 22000:2018 standards
Stored in non-toxic containers
Shipped in mineral oil-free boxes
All products guaranteed 100% free from magnesium stearate, nanoparticles (no legal opportunism), titanium dioxide, genetic engineering, artificial colours, flavours and sweeteners & added sugars

Effects

Vitamin B6 (Pyridoxine)

Vitamin B6 (pyridoxine) is the precursor of pyridoxal 5'-phosphate (PLP), one of the most important coenzymes in humans. As an active coenzyme form of vitamin B6, PLP enables about 100 enzymatic reactions and plays a central role in the metabolism of amino acids.

Vitamin B6 supports the breakdown of homocysteine and contributes to the normal synthesis of cysteine, an amino acid which serves as a central building block of important compounds such as coenzyme A, creatine, glutathione and taurine.

Vitamin B6 is also involved in the synthesis of the neurotransmitters serotonin, noradrenaline, dopamine and GABA. In addition, by modulating the effect of testosterone and oestrogen, vitamin B6 makes an important contribution to normal mental function and a healthy nervous system through these steroid hormones.

The influence of vitamin B6 in the nervous system extends to the synthesis of important components of the cell membrane, including myelin, a protective nerve layer, as well as phospholipids and sphingolipids.

Vitamin B6 is also important for energy metabolism, as it is involved in the metabolism of protein and glycogen. Glycogen is a carbohydrate that serves as an energy store in cells.

Directly Bioactive Vitamin B6 in the Form of PLP

In the form of pyridoxine, vitamin B6 does not have any direct biological activity. It must first be converted by the body into bioactive pyridoxal 5'-phosphate (PLP), a coenzyme form of vitamin B6, in order to be metabolically active.

Health Benefits of Vitamin B6

According to the European Food Safety Authority (EFSA), vitamin B6 contributes to:

Normal energy metabolism
Normal protein and glycogen metabolism
Normal functioning of the nervous system
Normal immune system functioning
Normal mental function
Hormonal activity regulation
Reducing tiredness and fatigue
Normal red blood cell formation
Normal homocysteine metabolism
Normal cysteine synthesis

Dosage

Recommended Dosage

Take 1 capsule (25mg vitamin B6 in the form of PLP) daily with 200ml water and a meal.

Daily Requirements

The requirement for vitamin B6 is between 1.2-1.8mg daily and increases according to protein intake.

Larger quantities of vitamin B6 are required by individuals who are pregnant, breastfeeding or of advanced age, during sports or stressful periods and with high-protein diets. Smoking and alcohol consumption, as well as many medications, further increase B6 needs. Moreover, this vitamin is very sensitive to heat and can be disintegrated during cooking or frying.

Food Supplement

Do not exceed the recommended dose. Food supplements cannot replace a balanced and varied diet. Keep out of reach of children.

Storage

Store in a cool, dry place away from direct sunlight and heat.

Ingredients: Bulking Agent (Gum Arabic), Capsule Shell (Hydroxypropyl Methylcellulose), Vitamin B6 (Pyridoxal 5′-Phosphate Monohydrate).

Contains: 120 capsules

Nutrition Information per Capsule		%NRV*
Vitamin B6 (PLP)	25mg	1786

* Nutrient Reference Value

Per capsule: 25mg vitamin B6
Per jar: 3000mg vitamin B6

Cofactors

All eight essential B vitamins work together. Numerous metabolic processes in the body require them; they can only achieve optimal functionality if each vitamin is in sufficient supply. Therefore, in many cases, it makes sense to supplement these vitamins together.

Product Details

German Pharmaceutical Number (PZN)	16850373
Origin	Filler: Premium gum arabic, gently processed in France
Production	In-house production in Europe, bottling and encapsulation in the EU according to HACCP, GMP/ISO 22000:2018 standards Finished products packaged in amber glass jars and stored in non-toxic containers Shipping in mineral oil-free boxes
Capsules	Plant-based cellulose (HPMC). Vegan Premium HPMC quality: Free from controversial additives such as carrageenans and PEG
Packaging	Amber glass jar to protect against light and oxidation (free from plasticisers and BPA)
To Reuse	Remove product label by soaking the jar in warm water for 5 minutes. Glue residue can be removed with dish soap

Laboratory Tests

The purity of our formulas is important to us. This is why we have both our raw ingredients as well as our finished products extensively tested by independent laboratories to confirm purity and active ingredient content. Here, we have provided the results of some of the tests carried out on this product.

MINERALS/
VITAMINS

See Tests

CONFORMITY STATEMENT

See Tests

Sunday Natural

Our Philosophy

For thousands of years, cultures all over the world have been using medicinal plants and nutritious foods to naturally foster and maintain vitality and good health.

With our products, we try to emulate this ancient wisdom as much as possible.

Consequently, our philosophy is simple: everything we do meets the highest standards of quality and purity; our focus is on organic and natural ingredients.

We follow this philosophy with meticulous care on all levels and down to every last detail.

Learn more.